<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2026 Workiva-->
<!--r:019b4b75-5053-7b9b-a5f1-65dc68401d07,g:72ea7a69-0ec8-473b-b324-dc8640f09098-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/CONSOLIDATEDBALANCESHEETS" xlink:type="simple" xlink:href="ccrn-20251231.xsd#CONSOLIDATEDBALANCESHEETS"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/CONSOLIDATEDBALANCESHEETS" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_019b4b75-5282-7329-bfe3-62496959b77e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_019b4b75-5282-7b3c-a118-f512b04d7f87" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_019b4b75-5282-7329-bfe3-62496959b77e" xlink:to="loc_us-gaap_StockholdersEquity_019b4b75-5282-7b3c-a118-f512b04d7f87" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_019b4b75-5282-7a0e-9160-42ed1790b852" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_019b4b75-5282-7329-bfe3-62496959b77e" xlink:to="loc_us-gaap_CommitmentsAndContingencies_019b4b75-5282-7a0e-9160-42ed1790b852" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_019b4b75-5282-7bf0-a166-65de78b05a46" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Liabilities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_019b4b75-5282-7329-bfe3-62496959b77e" xlink:to="loc_us-gaap_Liabilities_019b4b75-5282-7bf0-a166-65de78b05a46" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_019b4b75-5282-7520-bfb6-4dcecd695099" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_019b4b75-5282-7655-87ca-bc6fd3b4c998" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_019b4b75-5282-7520-bfb6-4dcecd695099" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_019b4b75-5282-7655-87ca-bc6fd3b4c998" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_019b4b75-5282-76c6-ac31-cd397d3b1c1f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_019b4b75-5282-7520-bfb6-4dcecd695099" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_019b4b75-5282-76c6-ac31-cd397d3b1c1f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxesReceivable_019b4b75-5282-70b2-9022-2e0dfcc200a1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxesReceivable"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_019b4b75-5282-7520-bfb6-4dcecd695099" xlink:to="loc_us-gaap_IncomeTaxesReceivable_019b4b75-5282-70b2-9022-2e0dfcc200a1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseCurrent_019b4b75-5282-74d9-95b0-130360087942" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PrepaidExpenseCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_019b4b75-5282-7520-bfb6-4dcecd695099" xlink:to="loc_us-gaap_PrepaidExpenseCurrent_019b4b75-5282-74d9-95b0-130360087942" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InsuranceSettlementsReceivableCurrent_019b4b75-5282-7063-9c36-b14d78420030" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InsuranceSettlementsReceivableCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_019b4b75-5282-7520-bfb6-4dcecd695099" xlink:to="loc_us-gaap_InsuranceSettlementsReceivableCurrent_019b4b75-5282-7063-9c36-b14d78420030" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsCurrent_019b4b75-5282-7319-9829-a1ea95e9cc44" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherAssetsCurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_019b4b75-5282-7520-bfb6-4dcecd695099" xlink:to="loc_us-gaap_OtherAssetsCurrent_019b4b75-5282-7319-9829-a1ea95e9cc44" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_019b4b75-5282-7ee0-a42f-f324eb53253a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_019b4b75-5282-72e3-9bc1-5c08bba909d9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_019b4b75-5282-7ee0-a42f-f324eb53253a" xlink:to="loc_us-gaap_CommonStockValue_019b4b75-5282-72e3-9bc1-5c08bba909d9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalCommonStock_019b4b75-5282-7dac-acb2-f8f62732ba37" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AdditionalPaidInCapitalCommonStock"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_019b4b75-5282-7ee0-a42f-f324eb53253a" xlink:to="loc_us-gaap_AdditionalPaidInCapitalCommonStock_019b4b75-5282-7dac-acb2-f8f62732ba37" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_019b4b75-5282-7261-83ac-fcddf472a553" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_019b4b75-5282-7ee0-a42f-f324eb53253a" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_019b4b75-5282-7261-83ac-fcddf472a553" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_019b4b75-5282-73bd-844c-d5fb9c798656" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_019b4b75-5282-7ee0-a42f-f324eb53253a" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_019b4b75-5282-73bd-844c-d5fb9c798656" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_019b4b75-5282-76b9-8839-6c11b57b64e5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableAndOtherAccruedLiabilitiesCurrent_019b4b75-5282-7fab-8545-15eb5f81eeaf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsPayableAndOtherAccruedLiabilitiesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_019b4b75-5282-76b9-8839-6c11b57b64e5" xlink:to="loc_us-gaap_AccountsPayableAndOtherAccruedLiabilitiesCurrent_019b4b75-5282-7fab-8545-15eb5f81eeaf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_019b4b75-5282-7b34-9dd3-07309274fd6b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_019b4b75-5282-76b9-8839-6c11b57b64e5" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_019b4b75-5282-7b34-9dd3-07309274fd6b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_019b4b75-5282-7d60-8fda-177b3791dd1f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_019b4b75-5282-76b9-8839-6c11b57b64e5" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_019b4b75-5282-7d60-8fda-177b3791dd1f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityCurrent_019b4b75-5282-78ab-a21f-55aea1c2f611" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_019b4b75-5282-76b9-8839-6c11b57b64e5" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityCurrent_019b4b75-5282-78ab-a21f-55aea1c2f611" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesCurrent_019b4b75-5282-73eb-8bed-0ac6e4a5a8b8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherLiabilitiesCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_019b4b75-5282-76b9-8839-6c11b57b64e5" xlink:to="loc_us-gaap_OtherLiabilitiesCurrent_019b4b75-5282-73eb-8bed-0ac6e4a5a8b8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_019b4b75-5282-72ce-9f02-039d11a07d4c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_019b4b75-5282-721b-b714-d4a2e16635f6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetsCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_019b4b75-5282-72ce-9f02-039d11a07d4c" xlink:to="loc_us-gaap_AssetsCurrent_019b4b75-5282-721b-b714-d4a2e16635f6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_019b4b75-5282-7618-abfc-868a6fb4906f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_019b4b75-5282-72ce-9f02-039d11a07d4c" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_019b4b75-5282-7618-abfc-868a6fb4906f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_019b4b75-5282-7107-8443-a51d00f34a1c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_019b4b75-5282-72ce-9f02-039d11a07d4c" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_019b4b75-5282-7107-8443-a51d00f34a1c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_019b4b75-5282-7464-b91f-38983b8a79c2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_019b4b75-5282-72ce-9f02-039d11a07d4c" xlink:to="loc_us-gaap_Goodwill_019b4b75-5282-7464-b91f-38983b8a79c2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_019b4b75-5282-710f-b1ac-a93c7301e85c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_019b4b75-5282-72ce-9f02-039d11a07d4c" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_019b4b75-5282-710f-b1ac-a93c7301e85c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxAssetsNet_019b4b75-5282-7f09-953e-d96a5f791b05" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredIncomeTaxAssetsNet"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_019b4b75-5282-72ce-9f02-039d11a07d4c" xlink:to="loc_us-gaap_DeferredIncomeTaxAssetsNet_019b4b75-5282-7f09-953e-d96a5f791b05" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InsuranceSettlementsReceivableNoncurrent_019b4b75-5282-7103-9675-8a11a254742c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InsuranceSettlementsReceivableNoncurrent"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_019b4b75-5282-72ce-9f02-039d11a07d4c" xlink:to="loc_us-gaap_InsuranceSettlementsReceivableNoncurrent_019b4b75-5282-7103-9675-8a11a254742c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_CloudComputingNoncurrent_019b4b75-5282-7133-b065-dce959fc03a4" xlink:href="ccrn-20251231.xsd#ccrn_CloudComputingNoncurrent"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_019b4b75-5282-72ce-9f02-039d11a07d4c" xlink:to="loc_ccrn_CloudComputingNoncurrent_019b4b75-5282-7133-b065-dce959fc03a4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCompensationPlanAssets_019b4b75-5282-77e4-b0e2-aa0a6a481146" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredCompensationPlanAssets"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_019b4b75-5282-72ce-9f02-039d11a07d4c" xlink:to="loc_us-gaap_DeferredCompensationPlanAssets_019b4b75-5282-77e4-b0e2-aa0a6a481146" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_019c2184-a2ed-7f39-ac83-b37bd68a7c56" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_019b4b75-5282-72ce-9f02-039d11a07d4c" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_019c2184-a2ed-7f39-ac83-b37bd68a7c56" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_019b4b75-5282-7a25-be4a-b2703b956794" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Liabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_019b4b75-5282-73ec-b94f-6fab760783c5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_019b4b75-5282-7a25-be4a-b2703b956794" xlink:to="loc_us-gaap_LiabilitiesCurrent_019b4b75-5282-73ec-b94f-6fab760783c5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_019b4b75-5282-7173-bd03-182a1eeff8dd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_019b4b75-5282-7a25-be4a-b2703b956794" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_019b4b75-5282-7173-bd03-182a1eeff8dd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_019b4b75-5282-7f8a-989c-dd9030d6c6f3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredIncomeTaxLiabilitiesNet"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_019b4b75-5282-7a25-be4a-b2703b956794" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_019b4b75-5282-7f8a-989c-dd9030d6c6f3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilityForClaimsAndClaimsAdjustmentExpense_019b4b75-5282-7b77-8012-8da49a493929" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilityForClaimsAndClaimsAdjustmentExpense"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_019b4b75-5282-7a25-be4a-b2703b956794" xlink:to="loc_us-gaap_LiabilityForClaimsAndClaimsAdjustmentExpense_019b4b75-5282-7b77-8012-8da49a493929" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent_019b4b75-5282-70b4-901e-d9e68241ccf2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilityForUncertainTaxPositionsNoncurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_019b4b75-5282-7a25-be4a-b2703b956794" xlink:to="loc_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent_019b4b75-5282-70b4-901e-d9e68241ccf2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredCompensationLiabilityClassifiedNoncurrent_019c218e-8079-72f9-8ead-e6252f893243" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredCompensationLiabilityClassifiedNoncurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_019b4b75-5282-7a25-be4a-b2703b956794" xlink:to="loc_us-gaap_DeferredCompensationLiabilityClassifiedNoncurrent_019c218e-8079-72f9-8ead-e6252f893243" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_019c218e-8079-73d5-a29f-50aecd0eaee0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_019b4b75-5282-7a25-be4a-b2703b956794" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_019c218e-8079-73d5-a29f-50aecd0eaee0" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/CONSOLIDATEDSTATEMENTSOFOPERATIONSANDCOMPREHENSIVELOSSINCOME" xlink:type="simple" xlink:href="ccrn-20251231.xsd#CONSOLIDATEDSTATEMENTSOFOPERATIONSANDCOMPREHENSIVELOSSINCOME"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/CONSOLIDATEDSTATEMENTSOFOPERATIONSANDCOMPREHENSIVELOSSINCOME" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_019b4b75-5282-79a3-8619-8e9852f34b22" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_019b4b75-5282-7999-9821-2c47e8d2c8a0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019b4b75-5282-79a3-8619-8e9852f34b22" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_019b4b75-5282-7999-9821-2c47e8d2c8a0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpenses_019b4b75-5282-7cd5-be42-4024fb9067c7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CostsAndExpenses"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_019b4b75-5282-79a3-8619-8e9852f34b22" xlink:to="loc_us-gaap_CostsAndExpenses_019b4b75-5282-7cd5-be42-4024fb9067c7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpenses_019b4b75-5282-77a5-86b0-01bdcc020c48" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CostsAndExpenses"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DirectOperatingCosts_019b4b75-5282-7072-a537-c7672595e31b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DirectOperatingCosts"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_019b4b75-5282-77a5-86b0-01bdcc020c48" xlink:to="loc_us-gaap_DirectOperatingCosts_019b4b75-5282-7072-a537-c7672595e31b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_019b4b75-5282-7794-bc8a-4a80015bd390" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_019b4b75-5282-77a5-86b0-01bdcc020c48" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_019b4b75-5282-7794-bc8a-4a80015bd390" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForDoubtfulAccounts_019b4b75-5282-70a3-a267-030643cd2672" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProvisionForDoubtfulAccounts"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_019b4b75-5282-77a5-86b0-01bdcc020c48" xlink:to="loc_us-gaap_ProvisionForDoubtfulAccounts_019b4b75-5282-70a3-a267-030643cd2672" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_019b4b75-5282-7134-bcd4-b7fb1e4d9b29" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_019b4b75-5282-77a5-86b0-01bdcc020c48" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_019b4b75-5282-7134-bcd4-b7fb1e4d9b29" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringCharges_019b4b75-5282-7870-ad30-80188f3f85ae" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestructuringCharges"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_019b4b75-5282-77a5-86b0-01bdcc020c48" xlink:to="loc_us-gaap_RestructuringCharges_019b4b75-5282-7870-ad30-80188f3f85ae" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetImpairmentCharges_019b4b75-5282-7ccf-8ec7-c0e51642f8de" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetImpairmentCharges"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_019b4b75-5282-77a5-86b0-01bdcc020c48" xlink:to="loc_us-gaap_AssetImpairmentCharges_019b4b75-5282-7ccf-8ec7-c0e51642f8de" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_LegalAndOtherLosses_019b4b75-5282-7d60-ac55-4ff455e92d5c" xlink:href="ccrn-20251231.xsd#ccrn_LegalAndOtherLosses"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_019b4b75-5282-77a5-86b0-01bdcc020c48" xlink:to="loc_ccrn_LegalAndOtherLosses_019b4b75-5282-7d60-ac55-4ff455e92d5c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_AcquisitionAndIntegrationRelatedCosts_019b4b75-5282-7a3d-87da-774bd3545eec" xlink:href="ccrn-20251231.xsd#ccrn_AcquisitionAndIntegrationRelatedCosts"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CostsAndExpenses_019b4b75-5282-77a5-86b0-01bdcc020c48" xlink:to="loc_ccrn_AcquisitionAndIntegrationRelatedCosts_019b4b75-5282-7a3d-87da-774bd3545eec" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_019b4b75-5282-7bc6-b4c0-90447b74063d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_019b4b75-5282-71c1-9987-429650f864cc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_019b4b75-5282-7bc6-b4c0-90447b74063d" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_019b4b75-5282-71c1-9987-429650f864cc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_019b4b75-5282-78a5-92f2-3e6d1be1ed6c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_019b4b75-5282-7bc6-b4c0-90447b74063d" xlink:to="loc_us-gaap_NetIncomeLoss_019b4b75-5282-78a5-92f2-3e6d1be1ed6c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5282-77e0-995e-94d1a9d0ce9e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_019b4b75-5282-71fe-af31-4a7fb198653a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5282-77e0-995e-94d1a9d0ce9e" xlink:to="loc_us-gaap_OperatingIncomeLoss_019b4b75-5282-71fe-af31-4a7fb198653a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseNonoperating_019b4b75-5282-7198-9b8a-73827821f729" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestExpenseNonoperating"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5282-77e0-995e-94d1a9d0ce9e" xlink:to="loc_us-gaap_InterestExpenseNonoperating_019b4b75-5282-7198-9b8a-73827821f729" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_019b4b75-5282-793e-8ae3-d1712b0e7bd7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5282-77e0-995e-94d1a9d0ce9e" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_019b4b75-5282-793e-8ae3-d1712b0e7bd7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_019b4b75-5282-7e91-85d6-9bb4fca6801c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5282-77e0-995e-94d1a9d0ce9e" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_019b4b75-5282-7e91-85d6-9bb4fca6801c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentIncomeInterest_019b4b75-5282-7c2f-9c38-0ac93f49a1dd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InvestmentIncomeInterest"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5282-77e0-995e-94d1a9d0ce9e" xlink:to="loc_us-gaap_InvestmentIncomeInterest_019b4b75-5282-7c2f-9c38-0ac93f49a1dd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_019b4b75-5282-78d4-9975-2c24bb88d16b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5282-7ec0-8fae-0e8bce0ec387" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_019b4b75-5282-78d4-9975-2c24bb88d16b" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5282-7ec0-8fae-0e8bce0ec387" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_019b4b75-5282-7b56-b049-2fab88e2bfbc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_019b4b75-5282-78d4-9975-2c24bb88d16b" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_019b4b75-5282-7b56-b049-2fab88e2bfbc" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/CONSOLIDATEDSTATEMENTSOFCASHFLOWS" xlink:type="simple" xlink:href="ccrn-20251231.xsd#CONSOLIDATEDSTATEMENTSOFCASHFLOWS"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/CONSOLIDATEDSTATEMENTSOFCASHFLOWS" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_019b4b75-5282-70c5-813b-e7a9da3012c3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019b4b75-5282-7ada-9b86-ff4e79ac9c19" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_019b4b75-5282-70c5-813b-e7a9da3012c3" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019b4b75-5282-7ada-9b86-ff4e79ac9c19" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_019b4b75-5282-76af-ae78-eda1003a21dc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_019b4b75-5282-70c5-813b-e7a9da3012c3" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_019b4b75-5282-76af-ae78-eda1003a21dc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-728c-8da8-e99a82a0d6bf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_019b4b75-5282-70c5-813b-e7a9da3012c3" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-728c-8da8-e99a82a0d6bf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_019b4b75-5282-75e0-b5f4-a16843d69cc3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_019b4b75-5282-70c5-813b-e7a9da3012c3" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_019b4b75-5282-75e0-b5f4-a16843d69cc3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-71d4-be00-8eb886c6d45d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_019b4b75-5282-7500-93bb-3a56ff3d577d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInOtherOperatingLiabilities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-71d4-be00-8eb886c6d45d" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_019b4b75-5282-7500-93bb-3a56ff3d577d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_019b4b75-5282-7a89-aecf-dfff39d3930c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-71d4-be00-8eb886c6d45d" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_019b4b75-5282-7a89-aecf-dfff39d3930c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_OperatingLeaseExpenseNonCash_019b4b75-5282-7b5d-90a1-2593ec8e84b6" xlink:href="ccrn-20251231.xsd#ccrn_OperatingLeaseExpenseNonCash"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-71d4-be00-8eb886c6d45d" xlink:to="loc_ccrn_OperatingLeaseExpenseNonCash_019b4b75-5282-7b5d-90a1-2593ec8e84b6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_ProvisionForDoubtfulAccountsAndOtherAllowances_019b4b75-5282-70cc-93bf-7311b6beab6b" xlink:href="ccrn-20251231.xsd#ccrn_ProvisionForDoubtfulAccountsAndOtherAllowances"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-71d4-be00-8eb886c6d45d" xlink:to="loc_ccrn_ProvisionForDoubtfulAccountsAndOtherAllowances_019b4b75-5282-70cc-93bf-7311b6beab6b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_019b4b75-5282-72bd-a4f1-c705acbbe559" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-71d4-be00-8eb886c6d45d" xlink:to="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_019b4b75-5282-72bd-a4f1-c705acbbe559" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_019b4b75-5282-7b10-9ca0-3bfe5b65be3b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-71d4-be00-8eb886c6d45d" xlink:to="loc_us-gaap_NetIncomeLoss_019b4b75-5282-7b10-9ca0-3bfe5b65be3b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_019b4b75-5282-78b9-9966-2875d261fcbe" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-71d4-be00-8eb886c6d45d" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_019b4b75-5282-78b9-9966-2875d261fcbe" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_019b4b75-5282-7480-a5ea-3a68ef3af79a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-71d4-be00-8eb886c6d45d" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_019b4b75-5282-7480-a5ea-3a68ef3af79a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable_019b4b75-5282-7ce8-a083-30fe492fcf98" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-71d4-be00-8eb886c6d45d" xlink:to="loc_us-gaap_IncreaseDecreaseInAccruedIncomeTaxesPayable_019b4b75-5282-7ce8-a083-30fe492fcf98" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_019b4b75-5282-79cb-9324-be455c5a8c90" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-71d4-be00-8eb886c6d45d" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_019b4b75-5282-79cb-9324-be455c5a8c90" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_IncreaseDecreaseInOperatingLeaseLiabilities_019b4b75-5282-709d-92c4-899bb38becb3" xlink:href="ccrn-20251231.xsd#ccrn_IncreaseDecreaseInOperatingLeaseLiabilities"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-71d4-be00-8eb886c6d45d" xlink:to="loc_ccrn_IncreaseDecreaseInOperatingLeaseLiabilities_019b4b75-5282-709d-92c4-899bb38becb3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_019b4b75-5282-7e75-94f8-274c0c1abe44" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensation"/>
    <link:calculationArc order="12" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-71d4-be00-8eb886c6d45d" xlink:to="loc_us-gaap_ShareBasedCompensation_019b4b75-5282-7e75-94f8-274c0c1abe44" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_019b4b75-5282-7b60-9480-9f31545abe71" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:calculationArc order="13" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-71d4-be00-8eb886c6d45d" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_019b4b75-5282-7b60-9480-9f31545abe71" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetImpairmentCharges_019b4b75-5282-7edf-9805-7c6d01adedb9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetImpairmentCharges"/>
    <link:calculationArc order="14" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-71d4-be00-8eb886c6d45d" xlink:to="loc_us-gaap_AssetImpairmentCharges_019b4b75-5282-7edf-9805-7c6d01adedb9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoncashIncomeExpense_019b4b75-5282-7f1b-8c41-360fa1a07132" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherNoncashIncomeExpense"/>
    <link:calculationArc order="15" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_019b4b75-5282-71d4-be00-8eb886c6d45d" xlink:to="loc_us-gaap_OtherNoncashIncomeExpense_019b4b75-5282-7f1b-8c41-360fa1a07132" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_019b4b75-5282-74ec-b603-87304646d573" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_ProceedsFromAcquisitionRelatedSettlements_019b4b75-5282-799c-baf1-12ef7dc1f814" xlink:href="ccrn-20251231.xsd#ccrn_ProceedsFromAcquisitionRelatedSettlements"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_019b4b75-5282-74ec-b603-87304646d573" xlink:to="loc_ccrn_ProceedsFromAcquisitionRelatedSettlements_019b4b75-5282-799c-baf1-12ef7dc1f814" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_019b4b75-5282-7666-b8f9-bd5466d1d9ab" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_019b4b75-5282-74ec-b603-87304646d573" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_019b4b75-5282-7666-b8f9-bd5466d1d9ab" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019b4b75-5282-7b1c-93c7-bb82d5dc396d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfSecuredDebt_019b4b75-5282-7202-935e-498601266459" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfSecuredDebt"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019b4b75-5282-7b1c-93c7-bb82d5dc396d" xlink:to="loc_us-gaap_RepaymentsOfSecuredDebt_019b4b75-5282-7202-935e-498601266459" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromLongTermLinesOfCredit_019b4b75-5282-731c-8983-538093771a7f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromLongTermLinesOfCredit"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019b4b75-5282-7b1c-93c7-bb82d5dc396d" xlink:to="loc_us-gaap_ProceedsFromLongTermLinesOfCredit_019b4b75-5282-731c-8983-538093771a7f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RepaymentsOfLongTermLinesOfCredit_019b4b75-5282-75e6-a0f3-75add9dada3d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RepaymentsOfLongTermLinesOfCredit"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019b4b75-5282-7b1c-93c7-bb82d5dc396d" xlink:to="loc_us-gaap_RepaymentsOfLongTermLinesOfCredit_019b4b75-5282-75e6-a0f3-75add9dada3d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_019b4b75-5282-7204-8d9b-83fb23a8bf2b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019b4b75-5282-7b1c-93c7-bb82d5dc396d" xlink:to="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_019b4b75-5282-7204-8d9b-83fb23a8bf2b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentForContingentConsiderationLiabilityFinancingActivities_019b4b75-5282-78a7-adc1-9ecd5544a1b6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentForContingentConsiderationLiabilityFinancingActivities"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019b4b75-5282-7b1c-93c7-bb82d5dc396d" xlink:to="loc_us-gaap_PaymentForContingentConsiderationLiabilityFinancingActivities_019b4b75-5282-78a7-adc1-9ecd5544a1b6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_019b4b75-5282-7b8b-8cc8-61686c5d7069" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019b4b75-5282-7b1c-93c7-bb82d5dc396d" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_019b4b75-5282-7b8b-8cc8-61686c5d7069" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_019b4b75-5282-737a-871f-3eae3bb1add6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProceedsFromPaymentsForOtherFinancingActivities"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_019b4b75-5282-7b1c-93c7-bb82d5dc396d" xlink:to="loc_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_019b4b75-5282-737a-871f-3eae3bb1add6" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/GoodwillTradeNamesandOtherIntangibleAssetsAcquiredIntangibleAssetsDetails" xlink:type="simple" xlink:href="ccrn-20251231.xsd#GoodwillTradeNamesandOtherIntangibleAssetsAcquiredIntangibleAssetsDetails"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/GoodwillTradeNamesandOtherIntangibleAssetsAcquiredIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019b4b75-5283-7a65-89cc-f9c35a1055e3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_019b4b75-5283-7b67-88a0-cda6d5634456" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019b4b75-5283-7a65-89cc-f9c35a1055e3" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_019b4b75-5283-7b67-88a0-cda6d5634456" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_019b4b75-5283-74c3-a20a-8e28511843b3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019b4b75-5283-7a65-89cc-f9c35a1055e3" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_019b4b75-5283-74c3-a20a-8e28511843b3" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/GoodwillTradeNamesandOtherIntangibleAssetsEstimatedAnnualAmortizationExpenseDetails" xlink:type="simple" xlink:href="ccrn-20251231.xsd#GoodwillTradeNamesandOtherIntangibleAssetsEstimatedAnnualAmortizationExpenseDetails"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/GoodwillTradeNamesandOtherIntangibleAssetsEstimatedAnnualAmortizationExpenseDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019b4b75-5283-74e1-9499-260bb9a56f51" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_019b4b75-5283-7179-ac1f-9f0d0686cdb4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019b4b75-5283-74e1-9499-260bb9a56f51" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_019b4b75-5283-7179-ac1f-9f0d0686cdb4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_019b4b75-5283-70a8-9af4-ff71c7f4ed8e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019b4b75-5283-74e1-9499-260bb9a56f51" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_019b4b75-5283-70a8-9af4-ff71c7f4ed8e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_019b4b75-5283-7b54-979a-79ee2f3c8086" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019b4b75-5283-74e1-9499-260bb9a56f51" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_019b4b75-5283-7b54-979a-79ee2f3c8086" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_019b4b75-5283-70cb-bfe7-2c46fa2e6564" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019b4b75-5283-74e1-9499-260bb9a56f51" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFive_019b4b75-5283-70cb-bfe7-2c46fa2e6564" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFive_019b4b75-5283-7482-8f28-38db38b9267e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFive"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019b4b75-5283-74e1-9499-260bb9a56f51" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFive_019b4b75-5283-7482-8f28-38db38b9267e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_019b4b75-5283-776a-9d10-c26827568b7f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_019b4b75-5283-74e1-9499-260bb9a56f51" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_019b4b75-5283-776a-9d10-c26827568b7f" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/GoodwillTradeNamesandOtherIntangibleAssetsGoodwillRollforwardDetails" xlink:type="simple" xlink:href="ccrn-20251231.xsd#GoodwillTradeNamesandOtherIntangibleAssetsGoodwillRollforwardDetails"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/GoodwillTradeNamesandOtherIntangibleAssetsGoodwillRollforwardDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_019b4b75-5283-7ff9-b6fe-a650d414e3e7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Goodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillGross_019b4b75-5283-7472-8712-04d9a0683e6b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GoodwillGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Goodwill_019b4b75-5283-7ff9-b6fe-a650d414e3e7" xlink:to="loc_us-gaap_GoodwillGross_019b4b75-5283-7472-8712-04d9a0683e6b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillImpairedAccumulatedImpairmentLoss_019b4b75-5283-7109-adf3-5d12a321dd1d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GoodwillImpairedAccumulatedImpairmentLoss"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Goodwill_019b4b75-5283-7ff9-b6fe-a650d414e3e7" xlink:to="loc_us-gaap_GoodwillImpairedAccumulatedImpairmentLoss_019b4b75-5283-7109-adf3-5d12a321dd1d" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/PropertyandEquipmentDetails" xlink:type="simple" xlink:href="ccrn-20251231.xsd#PropertyandEquipmentDetails"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/PropertyandEquipmentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_019b4b75-5283-7489-a720-04dd8691c74d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_019b4b75-5283-72c9-9193-5e348a1c0b10" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_019b4b75-5283-7489-a720-04dd8691c74d" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_019b4b75-5283-72c9-9193-5e348a1c0b10" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_019b4b75-5283-78e6-92a6-b784eed60a88" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_019b4b75-5283-7489-a720-04dd8691c74d" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_019b4b75-5283-78e6-92a6-b784eed60a88" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/BalanceSheetDetailsDetails" xlink:type="simple" xlink:href="ccrn-20251231.xsd#BalanceSheetDetailsDetails"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/BalanceSheetDetailsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InsuranceSettlementsReceivableNoncurrent_019b4b75-5283-7c6a-ac99-088339038587" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InsuranceSettlementsReceivableNoncurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InsuranceReceivableForMalpracticeNoncurrent_019b4b75-5283-7429-88e7-3ec4b40e99dc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InsuranceReceivableForMalpracticeNoncurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InsuranceSettlementsReceivableNoncurrent_019b4b75-5283-7c6a-ac99-088339038587" xlink:to="loc_us-gaap_InsuranceReceivableForMalpracticeNoncurrent_019b4b75-5283-7429-88e7-3ec4b40e99dc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_InsuranceRecoveryForWorkersCompensationNoncurrent_019b4b75-5283-7bc2-899f-298ef5023d75" xlink:href="ccrn-20251231.xsd#ccrn_InsuranceRecoveryForWorkersCompensationNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InsuranceSettlementsReceivableNoncurrent_019b4b75-5283-7c6a-ac99-088339038587" xlink:to="loc_ccrn_InsuranceRecoveryForWorkersCompensationNoncurrent_019b4b75-5283-7bc2-899f-298ef5023d75" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InsuranceSettlementsReceivableCurrent_019b4b75-5283-75f4-a862-be463ef5199d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InsuranceSettlementsReceivableCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_InsuranceReceivableforHealthCurrent_019b4b75-5283-7302-bb73-4b9cb12fbbf8" xlink:href="ccrn-20251231.xsd#ccrn_InsuranceReceivableforHealthCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InsuranceSettlementsReceivableCurrent_019b4b75-5283-75f4-a862-be463ef5199d" xlink:to="loc_ccrn_InsuranceReceivableforHealthCurrent_019b4b75-5283-7302-bb73-4b9cb12fbbf8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_InsuranceRecoveryForWorkersCompensationCurrent_019b4b75-5283-7c88-bc91-d54a9879715e" xlink:href="ccrn-20251231.xsd#ccrn_InsuranceRecoveryForWorkersCompensationCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InsuranceSettlementsReceivableCurrent_019b4b75-5283-75f4-a862-be463ef5199d" xlink:to="loc_ccrn_InsuranceRecoveryForWorkersCompensationCurrent_019b4b75-5283-7c88-bc91-d54a9879715e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InsuranceReceivableForMalpracticeCurrent_019b4b75-5283-7bb8-b861-d6a49d35ad04" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InsuranceReceivableForMalpracticeCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InsuranceSettlementsReceivableCurrent_019b4b75-5283-75f4-a862-be463ef5199d" xlink:to="loc_us-gaap_InsuranceReceivableForMalpracticeCurrent_019b4b75-5283-7bb8-b861-d6a49d35ad04" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_019b4b75-5283-7311-a7b5-3fa148905e9f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringReserveNoncurrent_019b4b75-5283-7cea-9fb0-b679f7bd5821" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestructuringReserveNoncurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherLiabilitiesNoncurrent_019b4b75-5283-7311-a7b5-3fa148905e9f" xlink:to="loc_us-gaap_RestructuringReserveNoncurrent_019b4b75-5283-7cea-9fb0-b679f7bd5821" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_OtherLiabilitiesMiscellaneousNoncurrent_019b4b75-5283-774d-89e3-63a6f87ac395" xlink:href="ccrn-20251231.xsd#ccrn_OtherLiabilitiesMiscellaneousNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherLiabilitiesNoncurrent_019b4b75-5283-7311-a7b5-3fa148905e9f" xlink:to="loc_ccrn_OtherLiabilitiesMiscellaneousNoncurrent_019b4b75-5283-774d-89e3-63a6f87ac395" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_019b4b75-5283-73f5-acef-beef742ba650" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_019b4b75-5283-7953-ae1d-96437bc73944" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_019b4b75-5283-73f5-acef-beef742ba650" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_019b4b75-5283-7953-ae1d-96437bc73944" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableTradeCurrent_019b4b75-5283-78f4-a09c-31ff0477ee64" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccountsPayableTradeCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_019b4b75-5283-73f5-acef-beef742ba650" xlink:to="loc_us-gaap_AccountsPayableTradeCurrent_019b4b75-5283-78f4-a09c-31ff0477ee64" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_SubcontractorPayableCurrent_019b4b75-5283-73f7-9b5c-e4032bdafc31" xlink:href="ccrn-20251231.xsd#ccrn_SubcontractorPayableCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_019b4b75-5283-73f5-acef-beef742ba650" xlink:to="loc_ccrn_SubcontractorPayableCurrent_019b4b75-5283-73f7-9b5c-e4032bdafc31" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_019b4b75-5283-7bb2-9e64-3dacb811c6d9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedSalariesCurrent_019b4b75-5283-7154-a185-aceb3c63a1c3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedSalariesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_019b4b75-5283-7bb2-9e64-3dacb811c6d9" xlink:to="loc_us-gaap_AccruedSalariesCurrent_019b4b75-5283-7154-a185-aceb3c63a1c3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedBonusesCurrent_019b4b75-5283-71f0-a6bd-87cad2a9dcd7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedBonusesCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_019b4b75-5283-7bb2-9e64-3dacb811c6d9" xlink:to="loc_us-gaap_AccruedBonusesCurrent_019b4b75-5283-71f0-a6bd-87cad2a9dcd7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WorkersCompensationLiabilityCurrent_019b4b75-5283-7027-b227-d95a0aadf995" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WorkersCompensationLiabilityCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_019b4b75-5283-7bb2-9e64-3dacb811c6d9" xlink:to="loc_us-gaap_WorkersCompensationLiabilityCurrent_019b4b75-5283-7027-b227-d95a0aadf995" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MalpracticeLossContingencyAccrualUndiscountedCurrent_019b4b75-5283-70b1-b73e-4d5d01752eb6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MalpracticeLossContingencyAccrualUndiscountedCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_019b4b75-5283-7bb2-9e64-3dacb811c6d9" xlink:to="loc_us-gaap_MalpracticeLossContingencyAccrualUndiscountedCurrent_019b4b75-5283-70b1-b73e-4d5d01752eb6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherEmployeeRelatedLiabilitiesCurrent_019b4b75-5283-74b5-be60-e97657964a58" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherEmployeeRelatedLiabilitiesCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_019b4b75-5283-7bb2-9e64-3dacb811c6d9" xlink:to="loc_us-gaap_OtherEmployeeRelatedLiabilitiesCurrent_019b4b75-5283-74b5-be60-e97657964a58" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedVacationCurrent_019b4b75-5283-795d-9ae6-d4ab22bb93df" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccruedVacationCurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_019b4b75-5283-7bb2-9e64-3dacb811c6d9" xlink:to="loc_us-gaap_AccruedVacationCurrent_019b4b75-5283-795d-9ae6-d4ab22bb93df" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilityForClaimsAndClaimsAdjustmentExpense_019b4b75-5283-7c46-bd10-cdc67a32d15b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LiabilityForClaimsAndClaimsAdjustmentExpense"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WorkersCompensationLiabilityNoncurrent_019b4b75-5283-78bb-b0c3-02e162bef523" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WorkersCompensationLiabilityNoncurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilityForClaimsAndClaimsAdjustmentExpense_019b4b75-5283-7c46-bd10-cdc67a32d15b" xlink:to="loc_us-gaap_WorkersCompensationLiabilityNoncurrent_019b4b75-5283-78bb-b0c3-02e162bef523" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MalpracticeLossContingencyAccrualUndiscountedNoncurrent_019b4b75-5283-7fd8-aa58-458cd78901b9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MalpracticeLossContingencyAccrualUndiscountedNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilityForClaimsAndClaimsAdjustmentExpense_019b4b75-5283-7c46-bd10-cdc67a32d15b" xlink:to="loc_us-gaap_MalpracticeLossContingencyAccrualUndiscountedNoncurrent_019b4b75-5283-7fd8-aa58-458cd78901b9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_019b4b75-5283-77ee-ab2a-59246b9cc3ea" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepositsAssetsNoncurrent_019b4b75-5283-73c1-ae2c-8ca7febf40de" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DepositsAssetsNoncurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherAssetsNoncurrent_019b4b75-5283-77ee-ab2a-59246b9cc3ea" xlink:to="loc_us-gaap_DepositsAssetsNoncurrent_019b4b75-5283-73c1-ae2c-8ca7febf40de" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredFinanceCostsNoncurrentNet_019b4b75-5283-7d30-b162-ba5c7ce5f8fb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredFinanceCostsNoncurrentNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherAssetsNoncurrent_019b4b75-5283-77ee-ab2a-59246b9cc3ea" xlink:to="loc_us-gaap_DeferredFinanceCostsNoncurrentNet_019b4b75-5283-7d30-b162-ba5c7ce5f8fb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_PostEmploymentBenefitsNoncurrent_019b4b75-5283-7013-9966-9912ab2ed9d1" xlink:href="ccrn-20251231.xsd#ccrn_PostEmploymentBenefitsNoncurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherAssetsNoncurrent_019b4b75-5283-77ee-ab2a-59246b9cc3ea" xlink:to="loc_ccrn_PostEmploymentBenefitsNoncurrent_019b4b75-5283-7013-9966-9912ab2ed9d1" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/LeasesOperatingLeaseLiabilityMaturityDetails" xlink:type="simple" xlink:href="ccrn-20251231.xsd#LeasesOperatingLeaseLiabilityMaturityDetails"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/LeasesOperatingLeaseLiabilityMaturityDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_019b4b75-5339-700b-9a20-0e118fe0127a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_019b4b75-5339-79f8-b429-488778d1dfa9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_019b4b75-5339-700b-9a20-0e118fe0127a" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_019b4b75-5339-79f8-b429-488778d1dfa9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_019b4b75-5339-7fb8-9198-626c82d96167" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_019b4b75-5339-700b-9a20-0e118fe0127a" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_019b4b75-5339-7fb8-9198-626c82d96167" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_019b4b75-5339-7650-8227-772fae138038" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_019b4b75-5339-700b-9a20-0e118fe0127a" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_019b4b75-5339-7650-8227-772fae138038" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_019b4b75-5339-709b-be26-99a7c94d4897" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_019b4b75-5339-700b-9a20-0e118fe0127a" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_019b4b75-5339-709b-be26-99a7c94d4897" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_019b4b75-5339-73cd-b8ed-194d09cbd337" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_019b4b75-5339-700b-9a20-0e118fe0127a" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_019b4b75-5339-73cd-b8ed-194d09cbd337" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_019b4b75-5339-7546-b340-31e185c5b404" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_019b4b75-5339-7f06-97cd-65966f89cffd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingLeaseLiability_019b4b75-5339-7546-b340-31e185c5b404" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_019b4b75-5339-7f06-97cd-65966f89cffd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_019b4b75-5339-715c-aff2-4978cac8d7ee" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingLeaseLiability_019b4b75-5339-7546-b340-31e185c5b404" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_019b4b75-5339-715c-aff2-4978cac8d7ee" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/LeasesOperatingLeaseLiabilityMaturityDetails_1" xlink:type="simple" xlink:href="ccrn-20251231.xsd#LeasesOperatingLeaseLiabilityMaturityDetails_1"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/LeasesOperatingLeaseLiabilityMaturityDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_019b4b75-5339-7568-a965-9f346e914e0b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_019b4b75-5339-79ab-8dec-b6a0b79733a1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_019b4b75-5339-7568-a965-9f346e914e0b" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_019b4b75-5339-79ab-8dec-b6a0b79733a1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_019b4b75-5339-7d1e-b8e0-ebd98197cd07" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_019b4b75-5339-7568-a965-9f346e914e0b" xlink:to="loc_us-gaap_OperatingLeaseLiability_019b4b75-5339-7d1e-b8e0-ebd98197cd07" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/IncomeTaxesComponentsofIncomeLossBeforeIncomeTaxesDetails" xlink:type="simple" xlink:href="ccrn-20251231.xsd#IncomeTaxesComponentsofIncomeLossBeforeIncomeTaxesDetails"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/IncomeTaxesComponentsofIncomeLossBeforeIncomeTaxesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5339-73bb-8f86-f78baa80e711" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_019b4b75-5339-7179-a1dc-987555004d84" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5339-73bb-8f86-f78baa80e711" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic_019b4b75-5339-7179-a1dc-987555004d84" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_019b4b75-5339-757a-b128-f79dc3e1ded6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5339-73bb-8f86-f78baa80e711" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign_019b4b75-5339-757a-b128-f79dc3e1ded6" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/IncomeTaxesComponentsofIncomeTaxExpenseBenefitDetails" xlink:type="simple" xlink:href="ccrn-20251231.xsd#IncomeTaxesComponentsofIncomeTaxExpenseBenefitDetails"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/IncomeTaxesComponentsofIncomeTaxExpenseBenefitDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_DeferredIncomeTaxExpenseBenefitExcludingForeignCurrencyImpact_019b4b75-5339-7ccb-93f7-5db59ad918ff" xlink:href="ccrn-20251231.xsd#ccrn_DeferredIncomeTaxExpenseBenefitExcludingForeignCurrencyImpact"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredFederalIncomeTaxExpenseBenefit_019b4b75-5339-72df-b81c-d86959097501" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredFederalIncomeTaxExpenseBenefit"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ccrn_DeferredIncomeTaxExpenseBenefitExcludingForeignCurrencyImpact_019b4b75-5339-7ccb-93f7-5db59ad918ff" xlink:to="loc_us-gaap_DeferredFederalIncomeTaxExpenseBenefit_019b4b75-5339-72df-b81c-d86959097501" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredStateAndLocalIncomeTaxExpenseBenefit_019b4b75-5339-7f99-a9a9-45b7ccfd1b75" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredStateAndLocalIncomeTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ccrn_DeferredIncomeTaxExpenseBenefitExcludingForeignCurrencyImpact_019b4b75-5339-7ccb-93f7-5db59ad918ff" xlink:to="loc_us-gaap_DeferredStateAndLocalIncomeTaxExpenseBenefit_019b4b75-5339-7f99-a9a9-45b7ccfd1b75" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredForeignIncomeTaxExpenseBenefit_019b4b75-5339-756d-adeb-c05024974997" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredForeignIncomeTaxExpenseBenefit"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ccrn_DeferredIncomeTaxExpenseBenefitExcludingForeignCurrencyImpact_019b4b75-5339-7ccb-93f7-5db59ad918ff" xlink:to="loc_us-gaap_DeferredForeignIncomeTaxExpenseBenefit_019b4b75-5339-756d-adeb-c05024974997" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_019b4b75-5339-7c8a-846a-3945804ac064" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CurrentIncomeTaxExpenseBenefit"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrentFederalTaxExpenseBenefit_019b4b75-5339-7365-a9b2-14df5a3dcd34" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CurrentFederalTaxExpenseBenefit"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_019b4b75-5339-7c8a-846a-3945804ac064" xlink:to="loc_us-gaap_CurrentFederalTaxExpenseBenefit_019b4b75-5339-7365-a9b2-14df5a3dcd34" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrentStateAndLocalTaxExpenseBenefit_019b4b75-5339-7c90-bb6e-425d57d1b118" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CurrentStateAndLocalTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_019b4b75-5339-7c8a-846a-3945804ac064" xlink:to="loc_us-gaap_CurrentStateAndLocalTaxExpenseBenefit_019b4b75-5339-7c90-bb6e-425d57d1b118" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrentForeignTaxExpenseBenefit_019b4b75-5339-7799-96a0-d230fdd5b9d1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CurrentForeignTaxExpenseBenefit"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_019b4b75-5339-7c8a-846a-3945804ac064" xlink:to="loc_us-gaap_CurrentForeignTaxExpenseBenefit_019b4b75-5339-7799-96a0-d230fdd5b9d1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_019b4b75-5339-7108-87e2-e30ff14a2b79" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_019b4b75-5339-7d08-8df6-a6f2e329e67c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CurrentIncomeTaxExpenseBenefit"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_019b4b75-5339-7108-87e2-e30ff14a2b79" xlink:to="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_019b4b75-5339-7d08-8df6-a6f2e329e67c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_DeferredIncomeTaxExpenseBenefitExcludingForeignCurrencyImpact_019b4b75-5339-7099-8461-f2ae885978a7" xlink:href="ccrn-20251231.xsd#ccrn_DeferredIncomeTaxExpenseBenefitExcludingForeignCurrencyImpact"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_019b4b75-5339-7108-87e2-e30ff14a2b79" xlink:to="loc_ccrn_DeferredIncomeTaxExpenseBenefitExcludingForeignCurrencyImpact_019b4b75-5339-7099-8461-f2ae885978a7" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/IncomeTaxesSignificantComponentsofDeferredTaxAssetsandLiabilitiesDetails" xlink:type="simple" xlink:href="ccrn-20251231.xsd#IncomeTaxesSignificantComponentsofDeferredTaxAssetsandLiabilitiesDetails"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/IncomeTaxesSignificantComponentsofDeferredTaxAssetsandLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilities_019b4b75-5339-7fcd-b05f-697d63f27059" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredIncomeTaxLiabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment_019b4b75-5339-7932-8a1e-3f67048ff218" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_019b4b75-5339-7fcd-b05f-697d63f27059" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment_019b4b75-5339-7932-8a1e-3f67048ff218" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets_019b4b75-5339-7316-91d6-19db96c82e8a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_019b4b75-5339-7fcd-b05f-697d63f27059" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets_019b4b75-5339-7316-91d6-19db96c82e8a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_DeferredTaxLiabilitiesRightOfUseAssets_019b4b75-5339-7f9c-8cec-5756cf8b17ff" xlink:href="ccrn-20251231.xsd#ccrn_DeferredTaxLiabilitiesRightOfUseAssets"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_019b4b75-5339-7fcd-b05f-697d63f27059" xlink:to="loc_ccrn_DeferredTaxLiabilitiesRightOfUseAssets_019b4b75-5339-7f9c-8cec-5756cf8b17ff" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesUndistributedForeignEarnings_019b4b75-5339-7473-8007-1af90f6c676c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxLiabilitiesUndistributedForeignEarnings"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_019b4b75-5339-7fcd-b05f-697d63f27059" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesUndistributedForeignEarnings_019b4b75-5339-7473-8007-1af90f6c676c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_019b4b75-5339-7d3d-8ad1-a6ef495868aa" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxAssetsLiabilitiesNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilities_019b4b75-5339-7041-9ce6-9672a62ddb07" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredIncomeTaxLiabilities"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_019b4b75-5339-7d3d-8ad1-a6ef495868aa" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilities_019b4b75-5339-7041-9ce6-9672a62ddb07" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsNet_019b4b75-5339-7285-b871-d9cb689f1fc5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxAssetsNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_019b4b75-5339-7d3d-8ad1-a6ef495868aa" xlink:to="loc_us-gaap_DeferredTaxAssetsNet_019b4b75-5339-7285-b871-d9cb689f1fc5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsGross_019b4b75-5339-722b-bd5a-99adf591dee6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxAssetsGross"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_DeferredTaxAssetsAccruedOtherLiabilitiesandPrepaidExpenses_019b4b75-5339-7bdb-a1a8-a5dbfc584f3e" xlink:href="ccrn-20251231.xsd#ccrn_DeferredTaxAssetsAccruedOtherLiabilitiesandPrepaidExpenses"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_019b4b75-5339-722b-bd5a-99adf591dee6" xlink:to="loc_ccrn_DeferredTaxAssetsAccruedOtherLiabilitiesandPrepaidExpenses_019b4b75-5339-7bdb-a1a8-a5dbfc584f3e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts_019b4b75-5339-76fc-aaea-0e45eda532e3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_019b4b75-5339-722b-bd5a-99adf591dee6" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAllowanceForDoubtfulAccounts_019b4b75-5339-76fc-aaea-0e45eda532e3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets_019b4b75-5339-73ec-bf90-47aaec38d354" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_019b4b75-5339-722b-bd5a-99adf591dee6" xlink:to="loc_us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets_019b4b75-5339-73ec-bf90-47aaec38d354" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_019b4b75-5339-71d3-8f6f-76c58bc1d727" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwards"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_019b4b75-5339-722b-bd5a-99adf591dee6" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_019b4b75-5339-71d3-8f6f-76c58bc1d727" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsOther_019b4b75-5339-7a44-80b1-1f40101154c0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsOther"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_019b4b75-5339-722b-bd5a-99adf591dee6" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsOther_019b4b75-5339-7a44-80b1-1f40101154c0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsEmployeeBenefits_019b4b75-5339-7a77-8462-b8fdc58ec5bb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsEmployeeBenefits"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_019b4b75-5339-722b-bd5a-99adf591dee6" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsEmployeeBenefits_019b4b75-5339-7a77-8462-b8fdc58ec5bb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_019b4b75-5339-73f6-a7a9-ca30931a8fe1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_019b4b75-5339-722b-bd5a-99adf591dee6" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_019b4b75-5339-73f6-a7a9-ca30931a8fe1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_DeferredTaxAssetsOperatingLeaseLiabilities_019b4b75-5339-72e6-886c-86c5504cb8e7" xlink:href="ccrn-20251231.xsd#ccrn_DeferredTaxAssetsOperatingLeaseLiabilities"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_019b4b75-5339-722b-bd5a-99adf591dee6" xlink:to="loc_ccrn_DeferredTaxAssetsOperatingLeaseLiabilities_019b4b75-5339-72e6-886c-86c5504cb8e7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxCreditCarryforwards_019b4b75-5339-7666-84a9-5a7bf886871c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxAssetsTaxCreditCarryforwards"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_019b4b75-5339-722b-bd5a-99adf591dee6" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxCreditCarryforwards_019b4b75-5339-7666-84a9-5a7bf886871c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsOther_019b4b75-5339-7b19-b8ef-20544317dba9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxAssetsOther"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_019b4b75-5339-722b-bd5a-99adf591dee6" xlink:to="loc_us-gaap_DeferredTaxAssetsOther_019b4b75-5339-7b19-b8ef-20544317dba9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_DeferredTaxAssetsDepreciation_019b4b75-5339-7efe-8779-5ef219c62678" xlink:href="ccrn-20251231.xsd#ccrn_DeferredTaxAssetsDepreciation"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsGross_019b4b75-5339-722b-bd5a-99adf591dee6" xlink:to="loc_ccrn_DeferredTaxAssetsDepreciation_019b4b75-5339-7efe-8779-5ef219c62678" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxLiabilities_019c8ff0-45bb-7e92-93c9-33f14c0aa403" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxLiabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsNet_019c8ff0-45bb-70b1-b72d-6dd57d8a2ce7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxAssetsNet"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxLiabilities_019c8ff0-45bb-7e92-93c9-33f14c0aa403" xlink:to="loc_us-gaap_DeferredTaxAssetsNet_019c8ff0-45bb-70b1-b72d-6dd57d8a2ce7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilities_019c8ff0-45bb-7623-a5f3-e49fc8baf6a7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredIncomeTaxLiabilities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxLiabilities_019c8ff0-45bb-7e92-93c9-33f14c0aa403" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilities_019c8ff0-45bb-7623-a5f3-e49fc8baf6a7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsNet_019b4b75-5339-74ec-afef-d2f5f9921214" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsGross_019b4b75-5339-7a05-908f-5d2f06610a89" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxAssetsGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_019b4b75-5339-74ec-afef-d2f5f9921214" xlink:to="loc_us-gaap_DeferredTaxAssetsGross_019b4b75-5339-7a05-908f-5d2f06610a89" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredTaxAssetsValuationAllowance_019b4b75-5339-78a7-b6bb-35b8dad9951c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DeferredTaxAssetsValuationAllowance"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_019b4b75-5339-74ec-afef-d2f5f9921214" xlink:to="loc_us-gaap_DeferredTaxAssetsValuationAllowance_019b4b75-5339-78a7-b6bb-35b8dad9951c" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/IncomeTaxesScheduleofIncomeTaxesPaidDetails" xlink:type="simple" xlink:href="ccrn-20251231.xsd#IncomeTaxesScheduleofIncomeTaxesPaidDetails"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/IncomeTaxesScheduleofIncomeTaxesPaidDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxesPaidNet_019c21f6-0cc5-72f2-993a-f6356b315928" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxesPaidNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxPaidFederalAfterRefundReceived_019c21f6-0cc5-7c7a-a75e-512a137489a9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxPaidFederalAfterRefundReceived"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxesPaidNet_019c21f6-0cc5-72f2-993a-f6356b315928" xlink:to="loc_us-gaap_IncomeTaxPaidFederalAfterRefundReceived_019c21f6-0cc5-7c7a-a75e-512a137489a9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxPaidStateAndLocalAfterRefundReceived_019c21f6-0cc5-7de5-8489-a65c415f7453" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxPaidStateAndLocalAfterRefundReceived"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxesPaidNet_019c21f6-0cc5-72f2-993a-f6356b315928" xlink:to="loc_us-gaap_IncomeTaxPaidStateAndLocalAfterRefundReceived_019c21f6-0cc5-7de5-8489-a65c415f7453" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxPaidForeignAfterRefundReceived_019c21f6-0cc5-706b-9e57-86656d75a04c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxPaidForeignAfterRefundReceived"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxesPaidNet_019c21f6-0cc5-72f2-993a-f6356b315928" xlink:to="loc_us-gaap_IncomeTaxPaidForeignAfterRefundReceived_019c21f6-0cc5-706b-9e57-86656d75a04c" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/IncomeTaxesReconciliationofIncomeTaxComputedAtUSFederalStatutoryRatetoIncomeTaxBenefitExpenseDetails" xlink:type="simple" xlink:href="ccrn-20251231.xsd#IncomeTaxesReconciliationofIncomeTaxComputedAtUSFederalStatutoryRatetoIncomeTaxBenefitExpenseDetails"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/IncomeTaxesReconciliationofIncomeTaxComputedAtUSFederalStatutoryRatetoIncomeTaxBenefitExpenseDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_019c21e2-be62-73ec-9d96-3adfabe2d671" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_019c21e2-be62-7e57-bc1a-ed9f250f2d28" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_019c21e2-be62-73ec-9d96-3adfabe2d671" xlink:to="loc_us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_019c21e2-be62-7e57-bc1a-ed9f250f2d28" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes_019c21e2-be62-7f3f-b3bb-28d3f4eecd07" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_019c21e2-be62-73ec-9d96-3adfabe2d671" xlink:to="loc_us-gaap_IncomeTaxReconciliationStateAndLocalIncomeTaxes_019c21e2-be62-7f3f-b3bb-28d3f4eecd07" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential_019c21e2-be62-74cd-aeaf-310e980515e7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_019c21e2-be62-73ec-9d96-3adfabe2d671" xlink:to="loc_us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential_019c21e2-be62-74cd-aeaf-310e980515e7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationCrossBorderTaxEffectAmount_019c21e2-be62-717a-aaad-6d94c8705a64" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationCrossBorderTaxEffectAmount"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_019c21e2-be62-73ec-9d96-3adfabe2d671" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationCrossBorderTaxEffectAmount_019c21e2-be62-717a-aaad-6d94c8705a64" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationTaxCredits_019c21e2-be62-7e2d-a731-803384cded3e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxReconciliationTaxCredits"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_019c21e2-be62-73ec-9d96-3adfabe2d671" xlink:to="loc_us-gaap_IncomeTaxReconciliationTaxCredits_019c21e2-be62-7e2d-a731-803384cded3e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_019c21e2-be62-79b2-99fb-a986d33f1a49" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_019c21e2-be62-73ec-9d96-3adfabe2d671" xlink:to="loc_us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_019c21e2-be62-79b2-99fb-a986d33f1a49" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpenseMealsAndEntertainment_019c21e2-be62-7f45-80f2-c3727603e91c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxReconciliationNondeductibleExpenseMealsAndEntertainment"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_019c21e2-be62-73ec-9d96-3adfabe2d671" xlink:to="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpenseMealsAndEntertainment_019c21e2-be62-7f45-80f2-c3727603e91c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOfficersCompensationAmount_019c21e2-be62-7ce2-b5b9-7c42794cfebd" xlink:href="ccrn-20251231.xsd#ccrn_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOfficersCompensationAmount"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_019c21e2-be62-73ec-9d96-3adfabe2d671" xlink:to="loc_ccrn_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOfficersCompensationAmount_019c21e2-be62-7ce2-b5b9-7c42794cfebd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpenseOther_019c21e2-be62-72b0-a085-2fdbc4b2fc9c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxReconciliationNondeductibleExpenseOther"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_019c21e2-be62-73ec-9d96-3adfabe2d671" xlink:to="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpenseOther_019c21e2-be62-72b0-a085-2fdbc4b2fc9c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationTaxContingencies_019c21e2-be62-7a2c-9f9d-9c079f038362" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxReconciliationTaxContingencies"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_019c21e2-be62-73ec-9d96-3adfabe2d671" xlink:to="loc_us-gaap_IncomeTaxReconciliationTaxContingencies_019c21e2-be62-7a2c-9f9d-9c079f038362" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxReconciliationOtherAdjustments_019c21e2-be62-76ba-9945-e1d7a08e5a89" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxReconciliationOtherAdjustments"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeTaxExpenseBenefit_019c21e2-be62-73ec-9d96-3adfabe2d671" xlink:to="loc_us-gaap_IncomeTaxReconciliationOtherAdjustments_019c21e2-be62-76ba-9945-e1d7a08e5a89" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_019c21e4-83ab-7103-8453-e4e749c325dd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EffectiveIncomeTaxRateContinuingOperations"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate_019c21e4-83ab-721d-8041-11d9a62a7855" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_019c21e4-83ab-7103-8453-e4e749c325dd" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate_019c21e4-83ab-721d-8041-11d9a62a7855" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes_019c21e4-83ab-731e-a4b4-18ac6f9d801d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_019c21e4-83ab-7103-8453-e4e749c325dd" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes_019c21e4-83ab-731e-a4b4-18ac6f9d801d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential_019c21e4-83ab-7782-9bdb-99677addc089" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_019c21e4-83ab-7103-8453-e4e749c325dd" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential_019c21e4-83ab-7782-9bdb-99677addc089" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationCrossBorderTaxEffectPercent_019c21e4-83ab-7fda-9374-153aff0d78d4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationCrossBorderTaxEffectPercent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_019c21e4-83ab-7103-8453-e4e749c325dd" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationCrossBorderTaxEffectPercent_019c21e4-83ab-7fda-9374-153aff0d78d4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationTaxCredits_019c21e4-83ab-77b1-9621-073db6ed8e32" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationTaxCredits"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_019c21e4-83ab-7103-8453-e4e749c325dd" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationTaxCredits_019c21e4-83ab-77b1-9621-073db6ed8e32" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance_019c21e4-83ab-7804-8ebc-f56732c3896a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_019c21e4-83ab-7103-8453-e4e749c325dd" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance_019c21e4-83ab-7804-8ebc-f56732c3896a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseMealsAndEntertainment_019c21e4-83ab-73bb-bac8-6fdfb3006079" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseMealsAndEntertainment"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_019c21e4-83ab-7103-8453-e4e749c325dd" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseMealsAndEntertainment_019c21e4-83ab-73bb-bac8-6fdfb3006079" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOfficersCompensationPercent_019c21e4-83ab-7da0-9301-fd778d357d87" xlink:href="ccrn-20251231.xsd#ccrn_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOfficersCompensationPercent"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_019c21e4-83ab-7103-8453-e4e749c325dd" xlink:to="loc_ccrn_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOfficersCompensationPercent_019c21e4-83ab-7da0-9301-fd778d357d87" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOther_019c21e4-83ab-7c3e-9fbb-5b5bbfc9ef8f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOther"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_019c21e4-83ab-7103-8453-e4e749c325dd" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOther_019c21e4-83ab-7c3e-9fbb-5b5bbfc9ef8f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationTaxContingencies_019c21e4-83ab-7eb6-a40a-bd771cfd31ce" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationTaxContingencies"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_019c21e4-83ab-7103-8453-e4e749c325dd" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationTaxContingencies_019c21e4-83ab-7eb6-a40a-bd771cfd31ce" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments_019c21e4-83ab-7ac7-b059-150b5b576338" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_019c21e4-83ab-7103-8453-e4e749c325dd" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationOtherAdjustments_019c21e4-83ab-7ac7-b059-150b5b576338" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/EarningsPerShareComponentsofNumeratorandDenominatorforComputationofBasicandDilutedEarningsperShareDetails" xlink:type="simple" xlink:href="ccrn-20251231.xsd#EarningsPerShareComponentsofNumeratorandDenominatorforComputationofBasicandDilutedEarningsperShareDetails"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/EarningsPerShareComponentsofNumeratorandDenominatorforComputationofBasicandDilutedEarningsperShareDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_019b4b75-5339-7979-acfe-43ac63771d0f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_019b4b75-5339-7c9e-84d0-bf43a78cd5be" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_019b4b75-5339-7979-acfe-43ac63771d0f" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_019b4b75-5339-7c9e-84d0-bf43a78cd5be" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_019b4b75-5339-7890-86bb-c5d09c93fe7e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_019b4b75-5339-7979-acfe-43ac63771d0f" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_019b4b75-5339-7890-86bb-c5d09c93fe7e" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.crosscountryhealthcare.com/role/SegmentDataOperatingSegmentsDetails" xlink:type="simple" xlink:href="ccrn-20251231.xsd#SegmentDataOperatingSegmentsDetails"/>
  <link:calculationLink xlink:role="http://www.crosscountryhealthcare.com/role/SegmentDataOperatingSegmentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_OperatingIncomeLossBeforeDAndAAcquisitionAndIntegrationRestructuringLegalImpairmentAndCorporateOverheard_019b4b75-5339-7c55-a35a-1126f2bc4ae1" xlink:href="ccrn-20251231.xsd#ccrn_OperatingIncomeLossBeforeDAndAAcquisitionAndIntegrationRestructuringLegalImpairmentAndCorporateOverheard"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DirectOperatingCosts_019b4b75-5339-7940-89a2-0cd6d40e6b53" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DirectOperatingCosts"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ccrn_OperatingIncomeLossBeforeDAndAAcquisitionAndIntegrationRestructuringLegalImpairmentAndCorporateOverheard_019b4b75-5339-7c55-a35a-1126f2bc4ae1" xlink:to="loc_us-gaap_DirectOperatingCosts_019b4b75-5339-7940-89a2-0cd6d40e6b53" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingOtherItemAmount_019b4b75-5339-74cd-abf2-bb4bc6958360" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SegmentReportingOtherItemAmount"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ccrn_OperatingIncomeLossBeforeDAndAAcquisitionAndIntegrationRestructuringLegalImpairmentAndCorporateOverheard_019b4b75-5339-7c55-a35a-1126f2bc4ae1" xlink:to="loc_us-gaap_SegmentReportingOtherItemAmount_019b4b75-5339-74cd-abf2-bb4bc6958360" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketingExpense_019b4b75-5339-79f3-aae0-ae5fe3e836cc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MarketingExpense"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ccrn_OperatingIncomeLossBeforeDAndAAcquisitionAndIntegrationRestructuringLegalImpairmentAndCorporateOverheard_019b4b75-5339-7c55-a35a-1126f2bc4ae1" xlink:to="loc_us-gaap_MarketingExpense_019b4b75-5339-79f3-aae0-ae5fe3e836cc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_LaborAndRelatedExpenseExcludingBenefitsExpense_019b4b75-5339-72c1-a786-0d054c529611" xlink:href="ccrn-20251231.xsd#ccrn_LaborAndRelatedExpenseExcludingBenefitsExpense"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ccrn_OperatingIncomeLossBeforeDAndAAcquisitionAndIntegrationRestructuringLegalImpairmentAndCorporateOverheard_019b4b75-5339-7c55-a35a-1126f2bc4ae1" xlink:to="loc_ccrn_LaborAndRelatedExpenseExcludingBenefitsExpense_019b4b75-5339-72c1-a786-0d054c529611" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForDoubtfulAccounts_019b4b75-5339-71e8-9a5b-cc23f934a42d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProvisionForDoubtfulAccounts"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ccrn_OperatingIncomeLossBeforeDAndAAcquisitionAndIntegrationRestructuringLegalImpairmentAndCorporateOverheard_019b4b75-5339-7c55-a35a-1126f2bc4ae1" xlink:to="loc_us-gaap_ProvisionForDoubtfulAccounts_019b4b75-5339-71e8-9a5b-cc23f934a42d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_019b4b75-5339-7f1e-91a8-3a8e619771b6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GeneralAndAdministrativeExpense"/>
    <link:calculationArc order="6" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ccrn_OperatingIncomeLossBeforeDAndAAcquisitionAndIntegrationRestructuringLegalImpairmentAndCorporateOverheard_019b4b75-5339-7c55-a35a-1126f2bc4ae1" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_019b4b75-5339-7f1e-91a8-3a8e619771b6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_019b4b75-5339-7c50-9847-e1927265a5cc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ccrn_OperatingIncomeLossBeforeDAndAAcquisitionAndIntegrationRestructuringLegalImpairmentAndCorporateOverheard_019b4b75-5339-7c55-a35a-1126f2bc4ae1" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_019b4b75-5339-7c50-9847-e1927265a5cc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_BenefitsExpense_019b4b75-5339-7c24-8483-8b6d63eb507a" xlink:href="ccrn-20251231.xsd#ccrn_BenefitsExpense"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_ccrn_OperatingIncomeLossBeforeDAndAAcquisitionAndIntegrationRestructuringLegalImpairmentAndCorporateOverheard_019b4b75-5339-7c55-a35a-1126f2bc4ae1" xlink:to="loc_ccrn_BenefitsExpense_019b4b75-5339-7c24-8483-8b6d63eb507a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5339-7ec8-9c41-c23b154dc3d0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_SegmentReportingUnallocatedCorporateExpenses_019b4b75-5339-75ce-9917-983249040633" xlink:href="ccrn-20251231.xsd#ccrn_SegmentReportingUnallocatedCorporateExpenses"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5339-7ec8-9c41-c23b154dc3d0" xlink:to="loc_ccrn_SegmentReportingUnallocatedCorporateExpenses_019b4b75-5339-75ce-9917-983249040633" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_019b4b75-5339-7a7b-b691-f12da65f6a77" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5339-7ec8-9c41-c23b154dc3d0" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_019b4b75-5339-7a7b-b691-f12da65f6a77" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_AcquisitionAndIntegrationRelatedCosts_019b4b75-5339-7fc4-ac3b-df758e2f7b8a" xlink:href="ccrn-20251231.xsd#ccrn_AcquisitionAndIntegrationRelatedCosts"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5339-7ec8-9c41-c23b154dc3d0" xlink:to="loc_ccrn_AcquisitionAndIntegrationRelatedCosts_019b4b75-5339-7fc4-ac3b-df758e2f7b8a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_LegalAndOtherLosses_019b4b75-5339-72a5-88a7-eb88faaf1e8d" xlink:href="ccrn-20251231.xsd#ccrn_LegalAndOtherLosses"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5339-7ec8-9c41-c23b154dc3d0" xlink:to="loc_ccrn_LegalAndOtherLosses_019b4b75-5339-72a5-88a7-eb88faaf1e8d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseNonoperating_019b4b75-5339-7540-9da2-e62df711eac7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestExpenseNonoperating"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5339-7ec8-9c41-c23b154dc3d0" xlink:to="loc_us-gaap_InterestExpenseNonoperating_019b4b75-5339-7540-9da2-e62df711eac7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentIncomeInterest_019b4b75-5339-7721-9a72-7056854270f3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InvestmentIncomeInterest"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5339-7ec8-9c41-c23b154dc3d0" xlink:to="loc_us-gaap_InvestmentIncomeInterest_019b4b75-5339-7721-9a72-7056854270f3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestructuringCharges_019b4b75-5339-71a7-b6bd-35ad9bee02b7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestructuringCharges"/>
    <link:calculationArc order="7" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5339-7ec8-9c41-c23b154dc3d0" xlink:to="loc_us-gaap_RestructuringCharges_019b4b75-5339-71a7-b6bd-35ad9bee02b7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_019b4b75-5339-7908-b887-91c0dfbd02ce" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5339-7ec8-9c41-c23b154dc3d0" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_019b4b75-5339-7908-b887-91c0dfbd02ce" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_ccrn_OperatingIncomeLossBeforeDAndAAcquisitionAndIntegrationRestructuringLegalImpairmentAndCorporateOverheard_019b4b75-5339-7d82-8476-86991e5a384d" xlink:href="ccrn-20251231.xsd#ccrn_OperatingIncomeLossBeforeDAndAAcquisitionAndIntegrationRestructuringLegalImpairmentAndCorporateOverheard"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5339-7ec8-9c41-c23b154dc3d0" xlink:to="loc_ccrn_OperatingIncomeLossBeforeDAndAAcquisitionAndIntegrationRestructuringLegalImpairmentAndCorporateOverheard_019b4b75-5339-7d82-8476-86991e5a384d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetImpairmentCharges_019b4b75-5339-7844-a6a2-6eeb50744fbe" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AssetImpairmentCharges"/>
    <link:calculationArc order="10" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5339-7ec8-9c41-c23b154dc3d0" xlink:to="loc_us-gaap_AssetImpairmentCharges_019b4b75-5339-7844-a6a2-6eeb50744fbe" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_019b4b75-5339-7a04-abed-92f9f5079ee8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_019b4b75-5339-7ec8-9c41-c23b154dc3d0" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_019b4b75-5339-7a04-abed-92f9f5079ee8" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
